BDBM50387175 CHEMBL2047991

SMILES FC(F)(F)c1cnc([nH]1)-c1cc(Oc2ccc(NC(=O)Nc3cc(ccc3Cl)C(F)(F)F)c(Cl)c2)ccn1

InChI Key InChIKey=NOMJOBPDCYIVEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387175   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Academy of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387175(CHEMBL2047991)
Affinity DataIC50: 35.9nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed