BDBM50387172 CHEMBL2047986

SMILES Cc1cccc(Cl)c1NC(=O)Nc1ccc(Oc2ccnc(c2)-c2ncc([nH]2)C(F)(F)F)cc1

InChI Key InChIKey=ICKHMDQGHZKNBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387172   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Academy of Military Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50387172(CHEMBL2047986)
Affinity DataIC50: 120nMAssay Description:Inhibition of C-Raf kinase-mediated phosphorylation of Mek using [33P]gammaATP after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed