BDBM50386452 CHEMBL2047680

SMILES NN=C(Cc1ccc(O)c(Br)c1)C(=O)NCCS

InChI Key InChIKey=AAIYXSVMDBVZTF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50386452   

TargetHistone deacetylase 1(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50386452(CHEMBL2047680)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50386452(CHEMBL2047680)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50386452(CHEMBL2047680)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant HDAC7 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50386452(CHEMBL2047680)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant HDAC8 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50386452(CHEMBL2047680)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Bordetella sp. (strain FB188) N-terminus His-tagged HDAH expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed