BDBM503863 US11034692, Compound 146::trans-N-[8-amino-6-(4-methyl-3-pyridyl)- 2,7-naphthyridin-3-yl]-2-(1- ethylsulfonylpyrazol-4- yl)cyclopropanecarboxamide

SMILES CCS(=O)(=O)n1cc(cn1)[C@@H]1C[C@H]1C(=O)Nc1cc2cc(nc(N)c2cn1)-c1cnccc1C

InChI Key InChIKey=NXFLJEJMNUQHRC-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503863   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM503863(trans-N-[8-amino-6-(4-methyl-3-pyridyl)- 2,7-napht...)Copy SMILESCopy InChI

Affinity DataKi:  0.0200nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/5/2021
Entry Details
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