BDBM50385737 CHEMBL2040999

SMILES CC(=O)c1ccc(Nc2ccc(cc2)C(F)(F)F)c(c1)C(O)=O

InChI Key InChIKey=VNHOHKNRJFYIDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50385737   

TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385737(CHEMBL2040999)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385737(CHEMBL2040999)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed