BDBM50385688 CHEMBL2041556

SMILES COc1ccc(Nc2cccc(c2)C(O)=O)c(c1)[N+]([O-])=O

InChI Key InChIKey=ZUDZDQKQVGCTJF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50385688   

TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385688(CHEMBL2041556)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385688(CHEMBL2041556)
Affinity DataIC50: 6.32E+3nMAssay Description:Inhibition of recombinant AKR1C1 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385688(CHEMBL2041556)
Affinity DataIC50: 5.56E+3nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385688(CHEMBL2041556)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of recombinant AKR1C4 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385688(CHEMBL2041556)
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibition of recombinant AKR1B1 assessed as NADP+ dependent reduction of DL-glyceraldehyde by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385688(CHEMBL2041556)
Affinity DataIC50: 3.93E+4nMAssay Description:Inhibition of recombinant AKR1B10 assessed as NADP+ dependent reduction of DL-glyceraldehyde by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50385688(CHEMBL2041556)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX2 expressed in baculovirus infected SF-21 cells assessed as formation of PGH2 from PGG2 using arachidonic acid as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed