BDBM50385180 CHEMBL2036871

SMILES Cn1c(nc2ccccc12)-c1ccc2c(n1)n(C)c(=O)n(C)c2=O

InChI Key InChIKey=JQGGHSNULNGIAQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50385180   

TargetAurora kinase B(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385180(CHEMBL2036871)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Aurora B using tetra(LRRWSLG) as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385180(CHEMBL2036871)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant AKT1 using GSK3 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 mins by scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385180(CHEMBL2036871)
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of recombinant FAK using poly(Glu,Tyr)4 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385180(CHEMBL2036871)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of recombinant VEGFR2 using poly(Glu,Tyr)4 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385180(CHEMBL2036871)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant PLK1 using RBERCHKtide as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed