BDBM50385177 CHEMBL2036868

SMILES COc1ccc(Nc2nccc(n2)-c2nc3ccccc3n2C)cc1

InChI Key InChIKey=QYUAAGZZXLCOSX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50385177   

TargetAurora kinase B(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385177(CHEMBL2036868)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of recombinant Aurora B using tetra(LRRWSLG) as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385177(CHEMBL2036868)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of recombinant AKT1 using GSK3 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 mins by scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385177(CHEMBL2036868)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant FAK using poly(Glu,Tyr)4 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385177(CHEMBL2036868)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of recombinant VEGFR2 using poly(Glu,Tyr)4 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50385177(CHEMBL2036868)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant PLK1 using RBERCHKtide as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed