BDBM50384888 CHEMBL2035810

SMILES Nc1ncnc(Nc2ccc(OCc3ccccn3)c(Cl)c2)c1-c1nc(CNC(=O)C=C)co1

InChI Key InChIKey=PRTPANUTPYMUDM-UHFFFAOYSA-N

Data  22 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50384888   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase STK11(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of LKB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IGF-1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of AMPKalpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 4nMAssay Description:Inhibition of HER4 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 22.4nMAssay Description:Inhibition of HER2 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of wild-type EGFR preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed