BDBM50384876 CHEMBL2035182

SMILES COCCOc1ccc2Nc3nccc(n3)-c3ccc(COC\C=C\CN(C)Cc1c2)s3

InChI Key InChIKey=GBFWZCHKVJJGKE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50384876   

TargetCyclin-dependent kinase 2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50384876(CHEMBL2035182)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant CDK2 using RbING as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384876(CHEMBL2035182)
Affinity DataIC50: 33nMAssay Description:Inhibition of TYK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50384876(CHEMBL2035182)
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant JAK1 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50384876(CHEMBL2035182)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384876(CHEMBL2035182)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant FLT3 using poly(Glu,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50384876(CHEMBL2035182)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant JAK3 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed