BDBM50384870 CHEMBL2035051

SMILES C(CN1CCCC1)Oc1ccc2Nc3nccc(n3)-c3cncc(COC\C=C\COCc1c2)c3

InChI Key InChIKey=UDJDOFKOOAFZRH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50384870   

TargetCyclin-dependent kinase 2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50384870(CHEMBL2035051)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant CDK2 using RbING as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50384870(CHEMBL2035051)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant JAK1 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50384870(CHEMBL2035051)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50384870(CHEMBL2035051)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant JAK3 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384870(CHEMBL2035051)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant FLT3 using poly(Glu,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384870(CHEMBL2035051)
Affinity DataIC50: 630nMAssay Description:Inhibition of TYK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed