BDBM50384725 CHEMBL2037209

SMILES Cc1cn(cn1)-c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1

InChI Key InChIKey=HAFMFNSFPWDDBC-UHFFFAOYSA-N

Data  29 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50384725   

LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Tel-fused FLT3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 15nMAssay Description:Inhibition of aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 14nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 53nMAssay Description:Inhibition of cSRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 116nMAssay Description:Inhibition of c-RAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of Tel-fused FGFR3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Tel-fused EPHA3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 7nMAssay Description:Inhibition of TRKA by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 54nMAssay Description:Inhibition of TRKB by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Tel-fused ALK in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of Tel-fused BMX in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Tel-fused FGFR4 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fgr(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of Tel-fused FGR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused FLT1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Tel-fused FMS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Tel-fused IGF1R in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInsulin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Tel-fused INSR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Tel-fused JNK2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 13nMAssay Description:Inhibition of Tel-fused KIT in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused MET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Tel-fused LYN in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 100nMAssay Description:Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 180nMAssay Description:Inhibition of Tel-fused RET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused RON in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Tel-fused SRC in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Tel-fused TIE1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused ZAP70 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed