BDBM50384651 CHEMBL2037111

SMILES O=C(Nc1ccccc1N1CCNCC1)c1csc(n1)-c1ccc2occc2c1

InChI Key InChIKey=YEUFJLDZFAPYER-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384651   

LigandPNGBDBM50384651(CHEMBL2037111)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant His-tagged CHK1 using biotin-RSGLYRSPSMPENLNRPR as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384651(CHEMBL2037111)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of CHK1 in human U2OS cells pretreated with hydroxyurea assessed as gamma-H2AX level after 2 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed