BDBM50384611 CHEMBL2036787::US9744172, Compound UNC00000573A

SMILES NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCCCc4ccccc4)nc23)CC1

InChI Key InChIKey=SSWDFFYWXHKOMP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50384611   

LigandPNGBDBM50384611(CHEMBL2036787 | US9744172, Compound UNC00000573A)
Affinity DataIC50: 38nMAssay Description:Inhibition of Axl using KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384611(CHEMBL2036787 | US9744172, Compound UNC00000573A)
Affinity DataIC50: 370nMAssay Description:Inhibition of Tyro3 using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384611(CHEMBL2036787 | US9744172, Compound UNC00000573A)
Affinity DataIC50: 10nMAssay Description:Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384611(CHEMBL2036787 | US9744172, Compound UNC00000573A)
Affinity DataIC50: 55nMAssay Description:The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
Go to US Patent