BDBM50384576 CHEMBL2036808

SMILES CCCCNc1ncc2c(nn(c2n1)CC3CCC(CC3)N)c4ccc(cc4)F

InChI Key InChIKey=OGEBRHQLRGFBNV-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50384576   

TargetTyrosine-protein kinase receptor TYRO3(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 48nMAssay Description:Inhibition of TYRO3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 37nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 141nMAssay Description:Inhibition of Mer autophosphorylation in human 697 cells pretreated for 1 hr before addition of phosphatase inhibitor measured by Western blot analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 37nMAssay Description:Inhibition of Axl using KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 48nMAssay Description:Inhibition of Tyro3 using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataIC50: 37nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)
Affinity DataKi:  4.30nMAssay Description:Inhibition of Mer using EFPIYDFLPAKKK-CONH2 as substrate by Michaelis-Menten equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed