BDBM50384526 CHEMBL2036421::US9073906, 3

SMILES CC(C)(C)OC(=O)N1CCCN(CC(=O)NC2C3CC4CC(C3)CC2C4)S1(=O)=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50384526   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50384526(CHEMBL2036421 | US9073906, 3)
Affinity DataIC50: 363nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50384526(CHEMBL2036421 | US9073906, 3)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50384526(CHEMBL2036421 | US9073906, 3)
Affinity DataIC50: 363nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed