BDBM50384473 CHEMBL2036222

SMILES CC(C)CC(=O)N(Cc1ccc(cc1)S(C)(=O)=O)c1cc(F)cc(c1)-c1nnn[nH]1

InChI Key InChIKey=SILQXRSMAJOSCL-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50384473   

TargetCytochrome P450 2C8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant CYP2C8 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 15 mins prior to substrate addition measured after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO cell membrane assessed as inhibition of PGD2-induced [35S]GTPgammaS binding after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384473(CHEMBL2036222)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed