BDBM50384411 CHEMBL2031503

SMILES Cc1nc(C(=O)N2CC(F)CC[C@H]2CNc2ccc(cn2)C(F)(F)F)c(s1)-c1ccccc1

InChI Key InChIKey=GJDYBOVHDFWUGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384411   

TargetOrexin receptor type 2(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50384411(CHEMBL2031503)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at OX2 receptor expressed in CHO cells assessed as inhibition of OXA-stimulated intracellular calcium mobilization after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50384411(CHEMBL2031503)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at OX1 receptor expressed in CHO cells assessed as inhibition of OXA-stimulated intracellular calcium mobilization after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed