BDBM50384351 CHEMBL2031020

SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(cc1C(=O)N1CCc2ccccc2C1)C(=O)NS(=O)(=O)c1ccc2N(CCc2c1)C(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=MMGKZUBGJDEIFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384351   

TargetApoptosis regulator Bcl-2(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50384351(CHEMBL2031020)
Affinity DataIC50: 280nMAssay Description:Inhibition in GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50384351(CHEMBL2031020)
Affinity DataIC50: 550nMAssay Description:Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed