BDBM50384342 CHEMBL2031010

SMILES Oc1c(Cl)cc(Cl)cc1S(=O)(=O)N(Cc1ccc(F)cc1)Cc1ccc(cc1)C(=O)N(Cc1ccc(F)cc1)Cc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=KUFRCLRVAYJMCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384342   

TargetApoptosis regulator Bcl-2(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50384342(CHEMBL2031010)
Affinity DataIC50: 35nMAssay Description:Inhibition in GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50384342(CHEMBL2031010)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed