BDBM50384175 CHEMBL2029903

SMILES Cn1cc(cc1C(=O)N2CCN(CC2)C)Nc3ncc4cc(n(c4n3)C5CCCC5)C(=O)N

InChI Key InChIKey=CXCXNZWXDOVZBA-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50384175   

TargetAurora kinase B(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50384175(CHEMBL2029903)
Affinity DataIC50: 11nMAssay Description:Inhibition of aurora B kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50384175(CHEMBL2029903)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50384175(CHEMBL2029903)
Affinity DataIC50: 28nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)