BDBM50384030 CHEMBL2032272::CHEMBL2079392

SMILES Nc1ncc(cc1-c1nc2ccc(Oc3ncccn3)cc2o1)-c1cnn(c1)C1CCNCC1

InChI Key InChIKey=OMRUNZARHPTHDL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50384030   

TargetG protein-coupled receptor kinase 5(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50384030(CHEMBL2079392 | CHEMBL2032272)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of GRK-5 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50384030(CHEMBL2079392 | CHEMBL2032272)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GRK-2 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50384030(CHEMBL2079392 | CHEMBL2032272)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed