BDBM50383731 CHEMBL2030394

SMILES Brc1ccc2oc3c(nc([nH]c3=O)[C@H]3CCCN3)c2c1

InChI Key InChIKey=IFSZNNCMCGMAHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383731   

LigandPNGBDBM50383731(CHEMBL2030394)
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminus Myc-tagged human CDC7 expressed in Escherichia coli by chemiluminescence assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50383731(CHEMBL2030394)
Affinity DataIC50: 104nMAssay Description:Inhibition of N-terminus His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50383731(CHEMBL2030394)
Affinity DataIC50: 4.59E+3nMAssay Description:Inhibition of CDC7 in human MDA-MB-231T cells assessed as inhibition of MCM2 phosphorylation at Ser53 after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed