BDBM50383659 CHEMBL2029849

SMILES COc1ccc2cc(\C=C3/SC(=NC3=O)c3ccc(Cl)cc3)ccc2c1

InChI Key InChIKey=LRXVSGVAHQRCJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383659   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50383659(CHEMBL2029849)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of 5-lipoxygenase in human polynuclear leukocytes assessed as inhibition of A23187-stimulated 5-LO product formation preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50383659(CHEMBL2029849)
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-lipoxygenase in cell free S100 freshly isolated human PMNL cells assessed as inhibition of A23187-stimulated 5-LO product formation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed