BDBM50383648 CHEMBL2029836

SMILES COc1ccc(\C=C2/SC(=NC2=O)c2cccc(Cl)c2)cc1

InChI Key InChIKey=PBKUWOLTZWHWGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383648   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50383648(CHEMBL2029836)
Affinity DataIC50: 180nMAssay Description:Inhibition of 5-lipoxygenase in human polynuclear leukocytes assessed as inhibition of A23187-stimulated 5-LO product formation preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50383648(CHEMBL2029836)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-lipoxygenase in cell free S100 freshly isolated human PMNL cells assessed as inhibition of A23187-stimulated 5-LO product formation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed