BDBM50383198 CHEMBL2032029

SMILES COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)O)n(-c5ccccc5)c4=O)nc3)ccnc2c1

InChI Key InChIKey=JQKLADMYWZPROY-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50383198   

TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50383198(CHEMBL2032029)
Affinity DataIC50: 45nMAssay Description:Inhibition of HGF-mediated c-Met autophosphorylation in human PC3 cells after 10 mins by quantitative electrochemiluminescent immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50383198(CHEMBL2032029)
Affinity DataKi:  0.800nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50383198(CHEMBL2032029)
Affinity DataKi:  932nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50383198(CHEMBL2032029)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of IGF1R by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed