BDBM50383162 CHEMBL2031884

SMILES CCNC(=O)c1ccc(cc1)-c1ccc2C(=O)N(CCN3CCC[C@H]3C)CCc2c1

InChI Key InChIKey=LBAKRWRQQGNMEB-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50383162   

LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human ERG by IonWorks assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-(R)-alpha-methylhistamine from human H3 receptor expressed in HEK293T cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi:  300nMAssay Description:Binding affinity to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity to alpha-2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi:  7.23E+3nMAssay Description:Binding affinity to H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383162(CHEMBL2031884)
Affinity DataKi:  1.01E+4nMAssay Description:Binding affinity to 5-HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed