BDBM50383019 CHEMBL2031273

SMILES COc1cc(cc(OC)c1OC)C(=O)NC(=O)Nc1cccc(NC(=O)c2ccccc2)c1

InChI Key InChIKey=QYEHHIQOIAJQAY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50383019   

TargetSmoothened homolog(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50383019(CHEMBL2031273)
Affinity DataIC50: 160nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50383019(CHEMBL2031273)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at Smo receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50383019(CHEMBL2031273)
Affinity DataIC50: 107nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50383019(CHEMBL2031273)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at Smo receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed