BDBM50382499 CHEMBL2022225

SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O

InChI Key InChIKey=OILANKFCQQDVRM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50382499   

TargetNeprilysin(Human)
Institute of Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50382499(CHEMBL2022225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant neutral endopeptidase using Ala-AMC as substrate after 20 to 40 mins by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Institute of Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50382499(CHEMBL2022225)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human recombinant aminopeptidase N using AbzdR-G-L-EDDnp as substrate after 20 to 40 mins by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Institute of Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50382499(CHEMBL2022225)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human recombinant AP-N ectopeptidase activity using alanine-MCA as substrate preincubated for 10 mins with substrate by fluorimetric an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeprilysin(Human)
Institute of Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50382499(CHEMBL2022225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant NEP ectopeptidase activity using Abz-dRGL-(EDDnp) as substrate preincubated for 10 mins with substrate by fluorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Institute of Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50382499(CHEMBL2022225)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant aminopeptidase N using Ala-Mca as substrate incubated for 10 mins prior to substrate addition measured for 40 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeprilysin(Human)
Institute of Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50382499(CHEMBL2022225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant neprilysin using Abz-dR-G-L-EDDnp as substrate incubated for 10 mins prior to substrate addition measured for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed