BDBM50382460 CHEMBL2023985::US10196373, Compound 27NA

SMILES COC(=O)c1cccc(c1)-c1ccc(cc1)-c1ccc(CN(C(=O)CN(C)S(=O)(=O)c2ccc(C)cc2)c2ccc(C(O)=O)c(O)c2)cc1

InChI Key InChIKey=LXXBORWQOCZOIL-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50382460   

TargetSignal transducer and activator of transcription 3(Human)
The Governing Council of The University of Toronto

US Patent
LigandPNGBDBM50382460(CHEMBL2023985 | US10196373, Compound 27NA)
Affinity DataIC50: 6.30E+4nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent

TargetSignal transducer and activator of transcription 3(Human)
The Governing Council of The University of Toronto

US Patent
LigandPNGBDBM50382460(CHEMBL2023985 | US10196373, Compound 27NA)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of fluorescein-labeled phosphotyrosine-peptide derived from the interleukin-6 receptor subunit gp130 from the STAT3 after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50382460(CHEMBL2023985 | US10196373, Compound 27NA)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of radioligand from the STAT1 after 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50382460(CHEMBL2023985 | US10196373, Compound 27NA)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of 5-carboxyfluorescein-labeled GpYLVLDKW from the STAT5b-SH2 domain after 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed