BDBM50382217 CHEMBL2023845

SMILES [#6]-[#7](-[#6])-[#6]-1-[#6]=[#6]-[#6]-2=[#6](-c3ccc(cc3-[#8]-[#6]-2=[#6]-1)-[#7](-[#6])-[#6])-c1ccc(cc1-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6](-[#7])=[#7]-[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#7]S(=O)(=O)c1cccc2cnccc12)-[#6](-[#7])=O)-[#6](-[#8])=O

InChI Key InChIKey=WVWKMLRXXWPJFD-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50382217   

TargetcGMP-dependent protein kinase 1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382217(CHEMBL2023845)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to His6-tagged recombinant human PKG1alpha by fluorescence anisotropy assay in absence of cGMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382217(CHEMBL2023845)
Affinity DataKd: <0.200nMAssay Description:Binding affinity to His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382217(CHEMBL2023845)
Affinity DataKd:  11nMAssay Description:Binding affinity to His6-tagged recombinant human p70S6K by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50382217(CHEMBL2023845)
Affinity DataKd:  5.30nMAssay Description:Binding affinity to His6-tagged recombinant human MSK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed