BDBM50381993 CHEMBL2022376

SMILES CC1CCCN(Cc2cc(Nc3nc(C)cn4c(cnc34)-c3cnn(CC(=O)NN4CC=CC=N4)c3)sn2)C1

InChI Key InChIKey=UEIDWGGSGUODLX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50381993   

TargetAurora kinase B(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50381993(CHEMBL2022376)
Affinity DataEC50:  951nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50381993(CHEMBL2022376)
Affinity DataIC50: 45nMAssay Description:Inhibition of aurora B kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50381993(CHEMBL2022376)
Affinity DataIC50: 638nMAssay Description:Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed