BDBM50381494 CHEMBL2017602

SMILES Cc1nc(nc2ccc(NC(=O)\C=C\c3ccc(Cl)cc3)cc12)N1CCC(O)(CC1)C1CCC1

InChI Key InChIKey=HBZBSOGZOJPPJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381494   

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381494(CHEMBL2017602)
Affinity DataIC50: 206nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381494(CHEMBL2017602)
Affinity DataIC50: 54nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed