BDBM50380000 CHEMBL258981

SMILES CN(O)C(=O)CCCP(O)(O)=O

InChI Key InChIKey=OXDGJHZVDJQJCC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50380000   

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50: 159nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycolicibacterium smegmatis (strain ATCC 700084 / ...)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50: 410nMAssay Description:Inhibition of Mycobacterium smegmatis DSM 43756 ATCC 19420 N-terminal his-tagged DXR expressed in XL1-blue Escherichia coli using NADPH and DXP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50: 48nMAssay Description:Inhibition of Escherichia coli DXR assessed as inhibition constant pre-incubated for 2 mins in presence of NADPH by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed