BDBM50379735 CHEMBL2011114

SMILES CC(C)N1Cc2c(nc(nc2NCc2ccc(cc2)C(F)(F)F)N2CCN(CC2)C(C)=O)C1=O

InChI Key InChIKey=APWGKCNSBHECJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50379735   

TargetP2X purinoceptor 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50379735(CHEMBL2011114)
Affinity DataIC50: 1.27E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in RLE cells assessed as inhibition of (alpha,beta)me-ATP-induced intracellular calcium level by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed