BDBM50379456 CHEMBL2012271

SMILES Fc1cccc(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)c1F

InChI Key InChIKey=NGNSDMCZYBVHJY-UHFFFAOYSA-N

Data  1 KI  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50379456   

TargetSodium channel protein type 5 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50379456(CHEMBL2012271)Copy SMILESCopy InChI

Affinity DataIC50: 70nMAssay Description:Antagonist activity at human NaV1.5 channel by patchXpress assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetSodium channel protein type 9 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50379456(CHEMBL2012271)Copy SMILESCopy InChI

Affinity DataIC50: 20nMAssay Description:Antagonist activity at human NaV1.7 channel by patchXpress assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Amgen

Curated by ChEMBL

LigandBDBM50379456(CHEMBL2012271)Copy SMILESCopy InChI

Affinity DataKi:  2.30E+3nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL