BDBM50379441 CHEMBL2012180

SMILES Fc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12

InChI Key InChIKey=JAUQXVXTUFWMRU-UHFFFAOYSA-N

Data  1 KI  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50379441   

TargetSodium channel protein type 5 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50379441(CHEMBL2012180)Copy SMILESCopy InChI

Affinity DataIC50: 30nMAssay Description:Antagonist activity at human NaV1.5 channel by patchXpress assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium channel protein type 9 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50379441(CHEMBL2012180)Copy SMILESCopy InChI

Affinity DataIC50: 60nMAssay Description:Antagonist activity at human NaV1.7 channel by patchXpress assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Amgen

Curated by ChEMBL

LigandBDBM50379441(CHEMBL2012180)Copy SMILESCopy InChI

Affinity DataKi:  2.50E+3nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL