BDBM50379281 CHEMBL2011504

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC(CC(O)=O)Cc3cccc4ccccc34)c2c1

InChI Key InChIKey=GXJGFPZJFOLIFD-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50379281   

TargetBcl-2-like protein 1(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50379281(CHEMBL2011504)
Affinity DataKd:  930nMAssay Description:Displacement of BakBH3 from Bcl-xL by DEL methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50379281(CHEMBL2011504)
Affinity DataKd:  930nMAssay Description:Binding affinity to human Bcl-xL after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50379281(CHEMBL2011504)
Affinity DataKd:  930nMAssay Description:Binding affinity to human Bcl-xL after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed