BDBM50379215 CHEMBL2011301::US9416123, 18

SMILES NC(=O)c1c(N)n(nc1-c1ccncc1)-c1ccccc1

InChI Key InChIKey=PJVOJOAOUWJXHF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50379215   

LigandPNGBDBM50379215(CHEMBL2011301 | US9416123, 18)
Affinity DataIC50: 4.80E+4nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

LigandPNGBDBM50379215(CHEMBL2011301 | US9416123, 18)
Affinity DataIC50: 6.40E+4nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Synovo

US Patent
LigandPNGBDBM50379215(CHEMBL2011301 | US9416123, 18)
Affinity DataIC50: 1.90E+4nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Synovo

US Patent
LigandPNGBDBM50379215(CHEMBL2011301 | US9416123, 18)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50379215(CHEMBL2011301 | US9416123, 18)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed