BDBM50379144 CHEMBL2012826::US8703811, 29

SMILES CCCCNC(=O)c1ccc(s1)-n1cnc2ccccc12

InChI Key InChIKey=VIFXYWNWCHHHMB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379144   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Genzyme

US Patent

LigandBDBM50379144(CHEMBL2012826 | US8703811, 29)Copy SMILESCopy InChI

Affinity DataIC50: 2.86E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/14/2014
Entry Details
Copy Entry DOIGo to US Patent

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TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
TBA

Curated by ChEMBL

LigandBDBM50379144(CHEMBL2012826 | US8703811, 29)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
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