BDBM50378824 CHEMBL1242367

SMILES CCNc1cc(N[C@@H]2CC[C@H](O)CC2)nc(Nc2ccc3n(Cc4ccccc4)ccc3c2)n1

InChI Key InChIKey=YVXCDLCJCIDFHE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50378824   

TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378824(CHEMBL1242367)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50378824(CHEMBL1242367)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged human CDK1/cyclinB expressed in sf9 cells using GST-pRb as substrate by [gamma-33P]ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50378824(CHEMBL1242367)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GST-tagged human CDK2/cyclinE expressed in sf9 cells using GST-pRb as substrate by [gamma-33P]ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50378824(CHEMBL1242367)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of GST-tagged human CDK4/cyclinD1 expressed in sf9 cells using GST-pRb as substrate by [gamma-33P]ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378824(CHEMBL1242367)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of CDK6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378824(CHEMBL1242367)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378824(CHEMBL1242367)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378824(CHEMBL1242367)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed