BDBM50378662 CHEMBL1204014

SMILES CN1CCN(CC1)C(=O)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2CCOCC2)N2CCOCC2)cc1

InChI Key InChIKey=ZDJOKGUTKMZKCX-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50378662   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL

LigandBDBM50378662(CHEMBL1204014)Copy SMILESCopy InChI

Affinity DataIC50: 1.40nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/28/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Wyeth Research

Curated by ChEMBL

LigandBDBM50378662(CHEMBL1204014)Copy SMILESCopy InChI

Affinity DataIC50: 0.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/28/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Wyeth Research

Curated by ChEMBL

LigandBDBM50378662(CHEMBL1204014)Copy SMILESCopy InChI

Affinity DataIC50: 9nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/28/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL