BDBM50378446 CHEMBL577238

SMILES CCOC(=O)Nc1cn2c(cc(cc2n1)-c1cnc(nc1)N(C)C)-c1nccc(C)n1

InChI Key InChIKey=RIPLRMVSSHSJMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378446   

TargetDNA gyrase subunit B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378446(CHEMBL577238)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378446(CHEMBL577238)
Affinity DataIC50: 6.22E+3nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed