BDBM50378437 CHEMBL578992

SMILES CCNC(=O)Nc1cn2c(cc(cc2n1)-c1cccnc1)-c1nc(cc(n1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=OIKPUVGIFBCWLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378437   

TargetDNA gyrase subunit B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378437(CHEMBL578992)
Affinity DataIC50: 242nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetDNA topoisomerase (ATP-hydrolyzing)(Streptococcus pneumoniae)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50378437(CHEMBL578992)
Affinity DataIC50: 745nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 parE after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed