BDBM50378386 CHEMBL582877

SMILES CC1(C)NC(Nc2cccc(Br)c2)=NC(N)=N1

InChI Key InChIKey=ODCAEXNEGXTNBY-UHFFFAOYSA-N

Data  11 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50378386   

Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataIC50: 328nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) expressed in CHO-K1 cells assessed as calcium flux after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine liver DHFR assessed as NADPH consumption during conversion of dihydrofolic acid to tetrahydrofolic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]LSD from 5-HT2B receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  265nMAssay Description:Displacement of [3H]LSD from 5-HT2C receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  389nMAssay Description:Displacement of [3H]LSD from 5-HT5A receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  660nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  696nMAssay Description:Displacement of [3H]LSD from 5-HT6 receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  783nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2A receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  1.53E+3nMAssay Description:Displacement of [3H]GR127543 from 5-HT1B receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  2.08E+3nMAssay Description:Displacement of [3H]LSD from 5-HT7A receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi:  2.66E+3nMAssay Description:Displacement of [3H]GR127543 from 5-HT1D receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-5-HT from 5-HT1E receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50378386(CHEMBL582877)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LY278584 from 5-HT3 receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed