BDBM50377844 CHEMBL258462

SMILES CN(C)c1cccc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CN(Cc3ccc(cc3)C(F)(F)F)C(=O)N2)c1

InChI Key InChIKey=OJFPQOAVNHLJCK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377844   

TargetCathepsin D(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377844(CHEMBL258462)
Affinity DataKi:  290nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377844(CHEMBL258462)
Affinity DataKi:  4.96E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed