BDBM50377843 CHEMBL259547

SMILES O[C@H](CNCc1cccc(c1)C(F)(F)F)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(Cc2ccccc2)C(=O)N1

InChI Key InChIKey=XIHBZDLDTUBMCD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50377843   

TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377843(CHEMBL259547)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human BACE1 by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377843(CHEMBL259547)
Affinity DataKi:  1.07E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377843(CHEMBL259547)
Affinity DataKi:  1.26E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed