BDBM50377318 CHEMBL257345

SMILES CC(C)COC(=O)N1CCC(C(O)=O)=C(CCc2ccc(OCCc3nc(oc3C)-c3ccccc3)cc2)C1

InChI Key InChIKey=KFTRRHRBOGHGRG-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50377318   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50377318(CHEMBL257345)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as luciferase activity by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50377318(CHEMBL257345)
Affinity DataEC50:  74nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells assessed as luciferase activity by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50377318(CHEMBL257345)
Affinity DataIC50: 255nMAssay Description:Binding affinity at human PPARalpha by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50377318(CHEMBL257345)
Affinity DataIC50: 110nMAssay Description:Binding affinity at human PPARalpha by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed