BDBM50377228 CHEMBL404289

SMILES Clc1ccc2oc(=O)n(CC(=O)N3CCCC(C3CN3CCOCC3)c3ccccc3)c2c1

InChI Key InChIKey=GYNUNSOVAWLPHA-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50377228   

TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50377228(CHEMBL404289)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50377228(CHEMBL404289)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50377228(CHEMBL404289)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50377228(CHEMBL404289)
Affinity DataKi:  40nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed