BDBM50376747 CHEMBL409247

SMILES C[n+]1cc(cc2c1cccc2)NC(=O)c3cccc(n3)C(=O)Nc4cc5ccccc5[n+](c4)C

InChI Key InChIKey=KPOOEJJPTYXNTN-UHFFFAOYSA-P

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50376747   

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50: 63nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50: 52nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed